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[caption id="attachment_22448" align="aligncenter" width="3840"]
Image Courtesy: Stranger Things[/caption]
Memory which is one of the fundamental functions of the brain is still largely a mystery to neuroscience researchers. Computers over the time have become more and more powerful, therefore researchers, over the years have used them to detect patterns and learn about key processes in the brain. Well, now researchers have discovered ways in which they can use AI techniques to boost memory.
An Illustration of the Closed-loop approach.[/caption]
Source: https://www.nature.com/articles/s41467-017-02753-0/figures/1
This research suggests that differences in specific individual’s neural activity can be studied, therefore making it easy to build models that modulate neural activity when there is a high chance that the brain won’t be able to encode successfully. This overall improves the performance by rescuing network activity. Similar research experiments have been tried in the past but with a difference. Most of the previous experiments were of open-loop design, meaning that stimulation was not delivered in response to ongoing neural activity or specific brain states.
Image Courtesy: Stranger Things[/caption]
Memory which is one of the fundamental functions of the brain is still largely a mystery to neuroscience researchers. Computers over the time have become more and more powerful, therefore researchers, over the years have used them to detect patterns and learn about key processes in the brain. Well, now researchers have discovered ways in which they can use AI techniques to boost memory.
The Experiment
In a recent paper in Nature, Michael J. Kahana and fellow researchers have investigated methods that improve memory. They used a closed-loop system to monitor and decode neural activity from brain recordings. After a series of experiments, they found that they could apply targeted stimulation to lateral temporal cortex (a part of the brain responsible for organizing sensory input, auditory perception, language and speech production) and rescue periods of poor memory encoding. The subjects enrolled for the study were epilepsy patients, who initially performed sessions of free recall which allowed researchers to collect data to build a multivariate classifier. The researchers fit a logistic regression classifiers to data, producing a model that maps features of neural activity to an output probability of later word recall. They have built a machine learning model that is specialized to each test subject. These classifiers monitor neural activity during memory encoding and trigger stimulation in real time in patterns of neural activity that have been learned by these models.Results show memory can be improved
The investigations have shown that it is also possible to improve later recall by targeting the lateral temporal cortex. Memory dysfunctions can also be addressed through such a system. Humans remember or forget information depending on neural events that happen during encoding. The study of Functional magnetic resonance imaging (fMRI) signals has shown that activity is different in cortical and subcortical regions which hints if the information is going to be forgotten or remembered. [caption id="attachment_22449" align="aligncenter" width="900"]
An Illustration of the Closed-loop approach.[/caption]
Source: https://www.nature.com/articles/s41467-017-02753-0/figures/1
This research suggests that differences in specific individual’s neural activity can be studied, therefore making it easy to build models that modulate neural activity when there is a high chance that the brain won’t be able to encode successfully. This overall improves the performance by rescuing network activity. Similar research experiments have been tried in the past but with a difference. Most of the previous experiments were of open-loop design, meaning that stimulation was not delivered in response to ongoing neural activity or specific brain states.


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